This is a professional line item. If you are unsure of the suitability of this supplement, please Book with our Naturopathic Doctor.

Calcium-d-glucarate assists in the detoxification process as it forms conjugates with unwanted estrogenic hormones and environmental toxins, which are then eliminated from the body instead of being reabsorbed. Also helps in the development and maintenance of bones and teeth.

Product Tech Sheet (PDF): calcium-d-glucarate-techsheet

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Calcium D-Glucarate is calcium bound to d-glucaric acid, which is a natural compound produced in
small amounts by the human body and is abundantly found in various plant foods such as broccoli,
cabbage, kale, apples, oranges, and grapefruit. Research shows that d-glucaric acid derivatives such
as calcium d-glucarate help support the body’s defense against toxins and excess sex hormones,
making calcium d-glucarate a potential agent in aiding detoxification.


In the GI tract, calcium d-glucarate is metabolized into three compounds, the most active being
D-glucaro-1,4-lactone. This metabolite increases detoxification by inhibiting β-glucuronidase, an
enzyme that can prevent proper and healthy excretion of potential toxins from the body. During liver detoxification some toxins and hormones such as estrogen, are cleared via glucuronidation – a process where glucuronic acid is attached to a toxin in order to create a less toxic conjugate
that can be readily eliminated by the body. In the case of liver detoxification, the substrates are most
often foreign xenobiotic substances such as drugs and pollutants, as well as endogenously produced
compounds like excess estrogens and androgens, mineralcorticoids, glucocorticoids, fatty acid
derivatives, retinoids, and bile acids. Theses toxins and hormones, bound to glucuronic acid, are now
ready to be safely eliminated.

• Supports detoxification of xenobiotics
• Supports healthy hormone metabolism and excretion

Recommended Dose: Adults: Take 2 capsules per day with meals, or as directed by your health care practitioner. Take a few hours before or after taking other medications or natural health products.

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We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product or Book with one of BodyCrafters Physicians / Naturopathic Doctors or a Certified Natural Product Advisor.


Designs For Health

About Designs for Health

Our Company Since 1989, Designs for Health has been the health care professional's trusted source for research-backed nutritional products of superior quality. By providing comprehensive support through our extensive product line, ongoing clinical education, and practice development programs, we are able to maximize the potential for successful health outcomes. Our wide array of added-value services not only set us apart, but indicate the depth of our commitment to you. Jonathan and Linda Lizotte, RD, CDN, founded Designs for Health in 1989 with a local team of nutritionists. Managing 22 Northeastern offices, the company's initial focus was to provide nutrition counseling services for the treatment of a variety of health conditions. The success of this endeavor grew, as did the demand for nutritional products to satisfy the specific treatment needs of the company's clinical nutritionists. Realizing that a genuine need existed for a line of nutritional supplements designed by health care professionals, for health care professionals, Designs for Health focused its efforts in this direction. Of utmost importance to the health professionals served by Designs for Health was ?? and still is ?? quality ingredients, efficacious doses, and company integrity. The formation of a Designs for Health branded supplement line led to mass requests from clinicians for further education and support. Advanced training courses were offered, dealing with nutritional approaches to chronic disease. To better serve its customers, Designs for Health responded in 1996 by directing its resources toward the establishment of 3 primary divisions: Professional Products, Research and Education, and Practice Development. With its roots in education, Designs for Health remains committed to providing the latest scientific nutrition research via innovative seminars and conferences. To this day, nutritionally-minded clinicians with ongoing clinical experiences shape the direction of the company. By holding itself to extremely high standards and delivering results, Designs for Health has established itself as one of the fastest growing manufacturers and distributors of nutritional supplements, selling exclusively to the health professionals market. Led by a talented and committed team of professionals whose ultimate goal is to help people lead healthier lives, Designs for Health delivers on its promise to provide the highest quality nutritional products available ?? and the dedicated relevant support needed to ensure optimal results.