Clinical Applications
- Source of probiotics
- Helps support intestinal/gastrointestinal health
- Could promote a favourable gut flora
Recommended Dose
Adults and adolescents 13 years+: Take one capsule once per day. If you are on antibiotics, take at least 2-3 hours before or after or ask your health care professional.
Lactobacillus acidophilus (La-14)
Lactobacillus acidophilus is (La-14) a beneficial bacterial strain that is normally found in the intestinal tract and mouth and is commercially used in dairy products for the production of acidophilus-type yogurt. L. acidophilus ferments various carbohydrates to produce lactic acid, which increases the absorption and bioavailability of minerals. This includes calcium, copper, magnesium and manganese. The production of lactic acid also promotes health by creating an inhospitable environment for invading microbes. L. acidophilus has been shown to protect intestinal cells by competing for adhesion space in the gut against harmful bacteria. The L. acidophilus strain in Ortho Biotic 100 has been specifically chosen because of its strong adherence and survival attributes in the GI tract.
Lactobacillus paracasei (Lpc-37)
Lactobacillus paracasei is a gastric acid-resistant strain that has been shown to protect against the harmful effects of bacteria by colonizing the intestinal tract. L. paracasei is a gastric acid-resistant strain and has been shown in vitro to withstand antibiotics such as Ciproflaxin and Vancomycin.
Bifidobacterium bifidum (Bb-02)
Bifidobacterium bifidum has been shown in culture studies to effectively compete with harmful bacteria such as E. coli, S. aureus and Camplylobacter jejuni, which suggests B. bifidum’s lactic acid and acetic acid production provides an antagonistic action against pathogens to help maintain microflora balance.
Bifidobacterium lactis (BI-04)
Bifidobacterium lactis is predominantly found in the colon. Studies examining dietary supplementation with B. lactis have shown that it supports GI health by reducing intestinal permeability.
Lactobacillus plantarum (Lp-115)
Lactobacillus plantarum is beneficial bacteria commonly found in fermented foods including sauerkraut, pickles, brined olives and sourdough. L. plantarum has been found to compete against strains of Clostridium difficile and Clostridium perfringens, due to the production of bacteriocins (lethal proteins) that inhibit bacterial growth in experimental animal models.
Lactobacillus rhamnosus (Lr-32)
Lactobacillus rhamnosus has been proven to have remarkable survivability in the acid and bile environments in the GI tract. L. rhamnosus is particularly useful because of its ability to adhere to cells, enhance microflora balance, and inhibit pathogen adherence.