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THYROID SYNERGY™ 120 Capsules Designs for Health

$52.99

This is a professional line item. If you are unsure of the suitability of this supplement, please Book with our Naturopathic Doctor.

Thyroid Synergy™ is designed to be an all-in-one thyroid support product that may benefit thyroid conditions. In just one product, it is now possible for the clinician to provide botanical and nutritional enhancement of thyroid hormone production, peripheral conversion of T4 to T3, as well as receptor function and recognition of thyroid hormones.

GLUTEN FREE/ DAIRY FREE/ VEGETARIAN/ NON-GMO

SKU: THM060-CN
NPN: 80050501
UPC Code: 879452000933

SKU: 879452000933 Categories: , ,

Thyroid Synergy™ is designed to be an all-in-one thyroid support product that may benefit thyroid conditions. In just one product, it is now possible for the clinician to provide botanical and nutritional enhancement of thyroid hormone production, peripheral conversion of T4 to T3, as well as receptor function and recognition of thyroid hormones.

SUPPORTIVE HERBS: AMERICAN GINSENG ROOT AND COLEUS FORSKOHLII
The non-stimulating adaptogenic botanical American Ginseng (Panax quinquefolius) may help control variations in cortisol. These variations may have deleterious effects on peripheral thyroid hormone conversion, as well as serum blood glucose and insulin levels, inducing dysglycemia.
WHY IS COLEUS FORSKOHLII EXTRACT HELPFUL FOR THYROID SUPPORT?
Coleus forskohlii’s active constituent forskohlin is a diterpene from the roots of Coleus forskohlii, known to directly activate the adenylate cyclase enzyme and raise cyclic AMP levels in many tissues. This is important because thyroid stimulating hormone (TSH) stimulates all steps in the synthesis and secretion of T3 and T4. The first step is the binding of TSH hormone to TSH receptors located on the basal membrane of thyroid epithelial cells, followed by elevation of cyclic AMP levels, and a subsequent cascade of phosphorylation reactions via activation of protein kinase A. The final step is the secretion of thyroid hormones T4 and T3 which again could not happen without cAMP.10 Hypothyroid patients need support in the area of fat metabolism. Coleus is known to reduce adipose assimilation and increase the lipolysis of fats. Coleus aids in the following functions:
1) Inhibiting the synthesis of adipose tissue
2) Increasing response to lipolytic hormones, which are produced in less quantity as we age
3) Utilizing stored fat.10 It may also play a role in aiding the production of digestive enzymes and supporting the immune system, both of which are helpful for hypothyroid patients.
TYROSINE, COPPER AND COLEUS FORSKOHLII
Cyclic AMP, copper and tyrosine are involved in the production of catecholamines such as dopamine and norepinephrine. This could be very helpful since hypothyroid patients are so susceptible to depression.10 Cyclic AMP is also a key player in regulating steroid hormone synthesis. These hormones include estrogen, progesterone and testosterone and depend on cholesterol for their making.10
CHROMIUM, ZINC AND MANGANESE
These minerals are needed for thyroid support to help control insulin since insulin blocks phosphorylation and therefore opposes the action of epinephrine and can impede thyroid hormone production.10 Chromium also helps to control cholesterol levels that often elevate in hypothyroid patients as well as control blood sugar levels which are challenged by poor adrenal and thyroid gland health.
N-ACETYL-L-TYROSINE AND IODINE
Tyrosine and iodine are intimately involved in the synthesis of thyroxine. N-acetyl-L-tyrosine is much more stable and better absorbed than L-tyrosine. Vitamin B2 supports these enzymatic conversions. A lack of iodine is a known contributing cause of goiter. Potassium iodide has been shown to help protect the thyroid gland from radiation damage. Potassium levels are often low in patients with poor thyroid and poor adrenal function. Potassium is necessary for getting thyroid hormone into our cells.
SELENIUM
Selenium is a key cofactor in the enzymatic conversion (ID-I enzyme) of T4, thyroxine hormone, to the more active T3, triiodothyronine. Selenium may also help protect the thyroid gland from mercury damage and from free radical damage . Selenium helps to make the powerfully protective enzyme glutathione peroxidase. One study looked at how selenium deficiency affected ID-I enzyme (I iodothyronine 5′-deiodinase) levels in the body. Selenium deficient rats had the following results: 1.) Hepatic and renal ID-I activities decreased by 60% and 50% respectively, serum levels of T3 reduced 36%, and T4 increased by 32%. 2.) GSH-Px (glutathione peroxidase) activities in the whole blood and liver decreased by 61% and 82% respectively. LPO (lipid peroxide) concentrations in serum and liver increased by 53% and 40% respectively.3 The results of a Graves’ disease study clearly indicated that supplementation with antioxidants in the treatment of Graves’ disease is justified, particularly those containing selenium.
VITAMIN A, ZINC AND SELENIUM
Studies tell us that TTR (transthyretin), an extracellular transfer protein in humans, is responsible for binding both T4 and T3 with a preference for T4. This protein also binds vitamin A, known to be important for thyroid function. TTR is an extracellular transport protein involved in the distribution of thyroid hormones and vitamin A. Hypothyroid patients often have a yellow-orange coloring to their skin because of very poor conversion of beta-carotene into vitamin A.6 Zinc is needed for this conversion. Significantly lower levels of zinc and selenium are found in the thyroids of patients with thyroid cancer, as compared to other thyroid patients.7 Zinc is likely as potent a thyroid antioxidant as selenium. Both of these minerals may help protect against heavy metals.
CAN SELENIUM SUPPLEMENTATION HELP THYROIDITIS?
Thyroiditis is inflammation of the thyroid gland. The most common type is autoimmune thyroiditis, in which, for complicated reasons, the body attacks the thyroid gland, decreasing its production of thyroid hormones. Selenium appears to have two essential functions related to thyroid health. First, it is a component of the detoxifying enzyme glutathione peroxidase. If selenium is unavailable, this enzyme does not work as effectively. Since glutathione peroxidase helps to quench free radicals, lowered activity may result in increased free-radical generation and increased damage to an already inflamed thyroid gland. Second, selenium is a key cofactor in the enzymatic conversion of thyroid hormone thyroxine (T4) to the more active triiodothyronine (T3), making selenium important for healthy thyroid function. In two recent studies, researchers tested this idea by giving subjects T4 with or without selenium supplements. In both studies the combined supplementation of T4 and selenium, compared with T4 only, was beneficial in decreasing the autoimmune-induced inflammation as measured by antibodies against thyroid peroxidase, particularly in those with very high antibody
levels. These two studies do show selenium is helpful and well-tolerated at the dose of 200 mcg daily.
Medicinal Ingredients (per capsule):
American ginseng (Panax quinquefolius-Root) (5% Ginsenosides)………………………………………..100 mg
N-Acetyl-L-tyrosine………………………………………………………………………………………………………….100 mg
Forskohlii (Plectranthus barbatus Root)20%Forskolin,75:1)………………………………………………….25 mg
Zinc (Zinc bisglycinate)…………………………………………………………………………………………………… 12.5 mg
Manganese (Manganese bisglycinate)…………………………………………………………………………………2.5 mg
Vitamin B2 (Riboflavin) ……………………………………………………………………………………………………2.5 mg
Vitamin A (Vitamin A palmitate)…………………………………………………………….302.2 mcg RAE (1000 IU)
Copper (Cupric bisglycinate) ………………………………………………………………………………………….250 mcg
Iodine (Potassium iodide)…………………………………………………………………………………………………50 mcg
Chromium (Chromic bisglycinate, Chromium nicotinate)…………………………………………………….25 mcg
Selenium (Selenomethionine)…………………………………………………………………………………………….25 mcg
Non-Medicinal Ingredients:
Microcrystalline cellulose, hypromellose, magnesium stearate (vegetable source).
Recommended Dose: Adults:
Take two capsules per day with meals a few hours before or after taking other medications, or as directed by your health care practitioner.

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Designs For Health

About Designs for Health

Since 1989, Designs for Health has stood as the go-to source for health professionals seeking top-tier, research-backed nutritional products. Their commitment is evident through an extensive product line, continuous clinical education, and programs aiding in practice development. Their diverse range of services not only sets them apart but showcases their unwavering dedication. Founded by Jonathan and Linda Lizotte, RD, CDN, with a team of local nutritionists, Designs for Health initially focused on nutrition counseling across 22 Northeastern offices. As the demand surged for specialized nutritional products, the company turned its attention to crafting supplements tailored by health care professionals for health care professionals. Their emphasis on quality ingredients, effective doses, and unwavering integrity remains paramount. The evolution into a branded supplement line sparked significant interest among clinicians, leading to comprehensive education and support initiatives, particularly addressing chronic diseases. In 1996, the company established three primary divisions: Professional Products, Research and Education, and Practice Development, to better serve its clientele. Rooted in education, Designs for Health continually provides the latest scientific nutritional research through pioneering seminars and conferences, shaped by nutritionally-focused clinicians with extensive clinical backgrounds. By upholding exceptionally high standards and delivering impactful results, Designs for Health has emerged as one of the fastest-growing manufacturers and distributors of nutritional supplements, exclusively catering to health professionals. Driven by a devoted team aspiring to enhance people's well-being, Designs for Health fulfills its commitment to offer the finest quality nutritional products and dedicated support for optimal results.
Trusted by health professionals since 1989, Designs for Health has been a reliable source for cutting-edge, research-backed nutritional products. Their extensive product line and commitment to ongoing education ensure optimal health outcomes. With a focus on quality, efficacy, and integrity, they stand as a leading choice for tailored supplements crafted by health experts, dedicated to enhancing wellness.
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