Cramp Matrix CytoMatrix

Designed to relieve a variety of muscle cramps and spasms, including premenstrual cramps, musculoskeletal pains and digestive disturbances.
  • Designed to relieve a variety of muscle cramps and spasms, including premenstrual cramps, musculoskeletal pains and digestive disturbances
  • Viburnum opulus and Scutellaria lateriflora are both traditionally known for their potent antispasmodic abilities
  • Zingiber officinale, Cinnamon aromaticum and Foeniculum vulgare have all been studied for their ability to improve premenstrual cramps and other menstrual symptoms
  • Zingiber officinale is standardized to 20% gingerol content, a potent active ingredient known to inhibit inflammation
  • Magnesium is delivered as an amino acid chelate for optimal stability and absorption in order to relax muscles and nervous tissue
  • Vitamin B6, in its active pyridoxal-5-phosphate form, improves serotonin and GABA production in order to modulate pain perception
Vegan. GMO, gluten, soy and dairy free.
Available in 120 vegetable capsules
SKU: 193229
NPN: 80094408
UPC Code: 871740001448

This is a professional line item. If you are unsure of the suitability of this supplement,         Book an appointment with one of our Naturopathic Doctors or consult with a  qualified healthcare practitioner.


Acute and chronic pain both involve a number of interplaying physiological mechanisms involving the nervous system, musculoskeletal system and immune system. While the most targeted pathways involve inflammation and pain receptors, smooth and skeletal muscle spasms are often involved. Clinically, there are a number of herbal preparations that can target these cramps and reduce pain.

For example, Viburnum opulus, more commonly known as cramp bark, is a herb that has traditionally been used to relieve all sorts of cramping, including abdominal muscle spasms and spasms associated with menstruation. Scutellaria lateriflora, commonly referred to as skullcap, is another traditionally used herb for its anti-spasmodic actions, yet there are many other evidence-based herbal remedies that have shown promise for the relief of cramps and spasms. Ginger is a prime example.

Many people associate ginger with its anti-nausea capabilities, but it has actually been studied extensively in the treatment of dysmenorrhea. Multiple trials confirm that ginger can effectively reduce menstrual pain when taken for the first 3-4 days of the menstrual cycle. In fact, ginger has been shown to be as effective as various anti-inflammatory medications such as ibuprofen or as a promising adjunctive therapy to NSAID medications. Additionally, research trials have found that ginger may decrease exercise-induced muscle soreness, improve post-exercise recovery, reduce migraine severity and duration, and reduce joint pain in osteoarthritis sufferers.

Cassia cinnamon is another herb that has been studied for its ability to improve dysmenorrhea symptoms. Multiple studies have shown that cassia cinnamon is capable of reducing the severity of menstrual pain, associated nausea and vomiting, while also reducing the amount of menstrual bleeding. Similar to ginger, cinnamon has been studied head-to- head against NSAID medications and shown to be just as effective with an impressive safety profile.

Finally, Foeniculum vulgare, also known as sweet fennel, is not just an effective remedy for digestive concerns such as constipation and irritable bowel syndrome. Indeed, fennel’s antispasmodic abilities provide these benefits, but it also has analgesic and anti-inflammatory properties which may collectively help to explain its effectiveness in clinical trials for reducing pain in dysmenorrhea.

Cramp Matrix combines traditional antispasmodic herbal extracts such as Viburnum opulus and Scutellaria lateriflora with evidence-based herbs such as Zingiber officinale, Cinnamomum aromaticum and Foeniculum vulgare in high-potency extracts and standardizations. Additional nutrients such as magnesium and vitamin B6 round out the formula for muscle relaxation and neurotransmitter regulation to modulate pain perception, respectively. Magnesium is delivered as an amino acid chelate for optimal stability and absorption, while vitamin B6 is included in its active pyridoxal-5- phosphate form.

Ingredient Amount
Crampbark extract (rhizome bark, Viburnum opulus) 10:1 62.5mg
Ginger extract (rhizome, Zingiber officinale) 10:1, 20% gingerols 50mg
Sweet Fennel extract (seed, Foeniculum vulgare subsp. vulgare var. dulce) 4:1 75mg
Cassia Cinnamon (branch bark, Cinnamomum aromaticum) 68.75mg
Skullcap (leaf, Scutellaria lateriflora) 75mg
Magnesium AlbionTM di-magnesium malate, TRAACSTM manganese bis-glycinate chelate* 37.5g
Vitamin B6 (pyridoxal-5-phosphate) 10mg
*Mineral chelate supplied by Albion Laboratories, Inc. AlbionTM and TRAACSTM are trademarks of Albion Laboratories,Inc. U.S Patents 6,706,904 7,838,042

Unit of Measure above: Each capsule

Non-Medicinal Ingredients: Vegetable-grade magnesium stearate, cellulose microcristalline, maltodextrin, citric acid, silica. Capsule: hypromellose.

Directions: Adults – Take 1 capsule, 4 times per day or as directed by a healthcare professional.

Duration of Use: For use beyond 2 weeks, consult a healthcare professional.

Indications: Cramp Matrix is a herbal formulation designed to relieve muscle cramps and spasms. It contains cramp bark, used in herbal medicine to relieve cramping, abdominal muscle spasms, and spasms associated with menstruation. It also features skullcap, traditionally used in herbal medicine to relieve restlessness, nervousness, and pain associated with menstruation, and sweet fennel, used in herbal medicine to help relieve pain associated with menstruation as well as digestive upset including bloating and flatulence.

Warnings: Do not use if safety seal is broken. Consult a healthcare professional prior to use especially if symptoms persist or worsen. Avoid taking with alcohol or products that increase drowsiness.

Contraindications: Do not use this product if you are pregnant or breastfeeding. Stop use if hypersensitivity/allergy occurs.

Known Adverse Reactions: Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness.


Cyto Matix

Why Choose Cyto-Matrix? We are 100% committed to helping you improve lives. Cyto-Matrix's products The excellent clinical results that are achieved with our products, combined with our honest and ethical approach, has earned Cyto-Matrix the trust of many of the most scrutinizing Canadian health care practitioners. We are appreciative and honoured that new clients of Cyto-Matrix quickly become loyal clients and are open to building a lasting relationship with us. Our philosophy is simple; purity, integrity, innovation: Purity Products are developed using the highest grade possible raw materials with vegetable capsules while minimizing the use of excipients. All products are manufactured in state-of-the-art, Good Manufacturing Practices (GMP)-compliant Canadian facilities, meeting or exceeding pharmaceutical and Health Canada standards. Third-Party tested with rigorous QA/QC. Integrity All formulations are researched and designed by Naturopathic Doctors based on Health Canada-approved, evidence based science. Products are fully licensed with approved Health Canada label claims. All associates are required to adhere to the high ethical standards of the organization. Customer Service Representatives will refer technical questions to staff doctors, with accurate, fast-as-possible turn around. Innovation Cyto-Matrix is continually researching and adding cutting-edge formulas to meet the unique and changing needs of your patients. Expertise and innovation are shared through seminars, blog articles and Practice Pearls to aid in professional development and continuing education. Regular feedback from practiticing professionals and our National Advisory Board is an integral part of our innovation. Do share your feedback and ideas! Quality Manufacturing Cyto-Matrix products are manufactured in state-of-the-art Canadian facilities in Quebec and Ontario. Cyto-Matrix's manufacturing facility These facilities hold valid Site Licenses as per the requirements of Health Canada's Natural Health Product Directorate. In accordance with these guidelines, sites must have procedures in place for distribution records and product recalls and for the handling, storage and delivery of their products. They must also demonstrate that they meet Good Manufacturing Practice (GMP) requirements. The Quality Assurance Department This department is responsible for the development of Standard Operating Procedures (SOP's). The main goal here is to ensure the integrity of the result of the finished product. All SOP's ensure compliance with GMP requirements. Other responsibilities include: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing The Quality Control Department Quality Control is done throughout the manufacturing process to ensure that the finished product meets the pre-determined specifications for micro-biological and physiological criteria. Raw materials are specifically tested to ensure the highest level of quality. The Validation Department Working closely with the QA and QC departments, the Validation department ensures compliance with all regulations and industry standards. In particular, the main responsibilities of this department are: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing Cyto-Matrix Inc. is dedicated to sourcing the highest quality of raw materials available on the global market. It is the combination of high quality raw materials and strictly adhered to GMP practices, which make Cyto-Matrix products of a superior class in the natural health products market.


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