Feature Summary
Deglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers. Licorice has been shown to inhibit several inflammatory enzymes, including both cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), decreasing the production of several potent inflammatory compounds, including prostaglandin E2, thromboxane B2, and leukotriene B4. Importantly, this inhibition is not due to glycyrrhizic acid, the component of licorice which has been removed in DGL, and which is associated with mineralocorticoid excess and hypertension. Another component of licorice, glabridin, has been shown to prevent lipopolysaccharide (LPS) induced production of inflammatory compounds, including nitric oxide and interleukin-1 beta, whereas glycyrrhizic acid has no effect.
Clinically, DGL has been shown to have comparable efficacy to cimetidine for both the healing and prevention of ulcer recurrences. Additionally, extracts of licorice have been shown to inhibit the adhesion of H. pylori to gastric mucosa, as well as the growth of antibiotic resistant strains, suggesting multiple mechanisms of action for its anti-ulcer benefit. The use of chewable tablets appears necessary for DGL’s efficacy, as it allows for distribution and absorption by the gastric mucosa.
Medicinal Ingredients
| Each Tablet Contains: |
|
| Deglycyrrhizinated Licorice 10:1 Extract (Glycyrrhiza glabra) (root) |
400 mg |
| Providing 4,000 mg crude herb licorice |
|
Non-Medicinal Ingredients
Xylitol, microcrystalline cellulose, aniseed, stearic acid, vegetable grade magnesium stearate (lubricant), silica, Stevia rebaudiana leaf.
Allergens:
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Recommended Use:
Chew 1 tablet 20 minutes prior to each meal, or as directed by a health care practitioner.
This is a professional line item. If you are unsure of the suitability of this supplement,
Book an appointment with one of our Naturopathic Doctors or consult with a qualified healthcare practitioner.
Alternative Option
Brand
Bioclinic Naturals
At Bioclinic Naturals, we offer an exclusive health care practitioner line of evidence-based natural health products.
Each formula is developed by the industry leading, outstanding scientists and health care practitioners on our Scientific Advisory Board to meet, and exceed, the needs of your patients.
Every great product starts with the best ingredients.
Our goal is to provide the best quality, tested raw materials. We have certified organic farmland in Canada’s Okanagan Valley, and whenever possible we grow our own plant-based ingredients. Any raw material we do not produce ourselves is subjected to the highest level of scrutiny to ensure the quality and purity.
We are Canada’s leading nutraceutical manufacturer.
We have state-of-the-art manufacturing facilities that include tabulating and softgel encapsulation. Our standards meet or surpasses the Canadian Good Manufacturing Practices (GMPs) established by the Natural and Non-Prescription Health Products Directorate (NNHPD) of the Canadian Federal Government, and Canadian Food Inspection Agency (CFIA) regulations. Our products also meet or exceed other international standards including the US Federal Drug Administration (FDA), the US Pharmacopeial Convention (USP), the Korean Ministry of Health and Welfare (MHW), and the Australian Therapeutic Goods Administration (TGA).
Our commitment to quality is reflected in the our investment in expanding our in-house Quality Control, Quality Assurance, and Research & Development departments, allowing us to verify the purity, potency, and efficacy of each and every product. We have advanced analytical technology and equipment, including HPLC and Mass Spectrometry, and can test for over 400 contaminants down to the molecular level. We adhere strictly to good laboratory practices (GLP), and our products are ISURA certified. This third party certification tests for non-GMO, contaminants, and identity.
Bioclinic Naturals’ focus is on clinical application for nutritional interventions and strategies for preventive medicine.
Our unique formulas meet practitioners’ needs for both condition-specific challenges and overall health enhancement. Our continual commitment to product quality in every stage of production for every product ensures that our products have earned the trust of practitioners and their patients.
We work closely with our Scientific Advisory Board to ensure that our products live up to their claims. Their scientific investigation focuses on the clinical application of our products, as well as nutritional interventions and strategies for preventive medicine.
At Bioclinic Naturals, we don’t just say that we provide the most effective natural health products – we prove it. We have the science and clinical research to back up our products for quality, potency, and effectiveness.
