Description
Aesculus hippocastanum, also known as Horse Chestnut, is a herb traditionally used to improve symptoms of chronic venous insufficiency (CVI) such as hemorrhoids and varicose veins. CVI leads to symptoms of itching, pain, discoloration and edema in the legs, creating both medical and aesthetic concerns. Modern research has confirmed that the active ingredient responsible for improving blood vessel integrity is known as escin. Escin has been found to increase nitric oxide production within the endothelial cells, thereby improving blood flow.
Clinical trials have found that horse chestnut extract can reduce pain and leg swelling associated with CVI and also significant reduction in symptoms, bleeding, and improvements in endoscopic evaluations in those with hemorrhoids. One trial showed that 82% of subjects had hemorrhoid improvements compared to only 32% in placebo, with most benefits acutely apparent within just six days of starting supplementation. Conversely, many studies for CVI find that maximum benefits occur within 1-3 months of supplementation. The evidence-based dose for Aesculus hippocastanum appears to be mostly dependent on escin content, which should reach a minimum 150mg per day, rather than the dried herb equivalent or total extract amount.
Horse Chestnut from Cyto-Matrix contains 375mg of Aesculus hippocastanum seed extract, standardized to contain a minimum of 20% escin content (75mg) per vegetable capsule. Horse Chestnut is also guaranteed to be free of esculin, a coumarin compound that can cause gastric distress in significant amounts. Each bottle of Horse Chestnut contains 90 vegetable capsules.
Horse Chestnut is a part of the Cyto-Matrix Herbal Matrix Series, containing sustainably sourced, traceable, and GMO free herbs with potent therapeutic properties. Each herb is extracted and tested to ensure the standardization of active ingredients, ultimately leading to efficacious, predictable and reliable products. The Cyto-Matrix Herbal Matrix Series of herbal extracts is beneficial for both the health of individuals, and also the health of our planet and future generations.
Ingredients
Horse-chestnut extract (seed, Aesculus hippocastanum) 375mg
Aescin 20%, 5:1, DHE 1875mg
Euromed Phytoproof *PhytoProof® is a registered trademark of Euromed USA, Inc
Unit of Measure above: Each capsule
Non-Medicinal Ingredients: Vegetable-grade magnesium stearate, microcrystalline cellulose, brown rice flour. Capsule: hypromellose.
Directions & Cautions
Indications: Traditionally used in Herbal Medicine to help treat haemorrhoids. Used in Herbal Medicine to help treat varicose veins, chronic venous insufficiency and associated symptoms.
Directions: Adults – Take 1 capsule, 1-2 times per day or as directed by a healthcare professional.
Warnings: Do not use if safety seal is broken. Consult a healthcare professional prior to use, especially if you are pregnant or breastfeeding. Consult a healthcare professional if symptoms persist or worsen.
Known Adverse Reactions: Some people may experience headache, dizziness, gastric irritation, or itchiness.
Brand
Cyto Matix
Why Choose Cyto-Matrix?
We are 100% committed to helping you improve lives.
Cyto-Matrix's products
The excellent clinical results that are achieved with our products, combined with our honest and ethical approach, has earned Cyto-Matrix the trust of many of the most scrutinizing Canadian health care practitioners. We are appreciative and honoured that new clients of Cyto-Matrix quickly become loyal clients and are open to building a lasting relationship with us.
Our philosophy is simple; purity, integrity, innovation:
Purity
Products are developed using the highest grade possible raw materials with vegetable capsules while minimizing the use of excipients.
All products are manufactured in state-of-the-art, Good Manufacturing Practices (GMP)-compliant Canadian facilities, meeting or exceeding pharmaceutical and Health Canada standards.
Third-Party tested with rigorous QA/QC.
Integrity
All formulations are researched and designed by Naturopathic Doctors based on Health Canada-approved, evidence based science.
Products are fully licensed with approved Health Canada label claims.
All associates are required to adhere to the high ethical standards of the organization.
Customer Service Representatives will refer technical questions to staff doctors, with accurate, fast-as-possible turn around.
Innovation
Cyto-Matrix is continually researching and adding cutting-edge formulas to meet the unique and changing needs of your patients.
Expertise and innovation are shared through seminars, blog articles and Practice Pearls to aid in professional development and continuing education.
Regular feedback from practiticing professionals and our National Advisory Board is an integral part of our innovation. Do share your feedback and ideas!
Quality Manufacturing
Cyto-Matrix products are manufactured in state-of-the-art Canadian facilities in Quebec and Ontario.
Cyto-Matrix's manufacturing facility
These facilities hold valid Site Licenses as per the requirements of Health Canada's Natural Health Product Directorate. In accordance with these guidelines, sites must have procedures in place for distribution records and product recalls and for the handling, storage and delivery of their products. They must also demonstrate that they meet Good Manufacturing Practice (GMP) requirements.
The Quality Assurance Department
This department is responsible for the development of Standard Operating Procedures (SOP's). The main goal here is to ensure the integrity of the result of the finished product. All SOP's ensure compliance with GMP requirements. Other responsibilities include:
Editing of protocols and installation, operation and performance qualification implementation
Validation of HVAC, purified water and other systems
Validation of production of lab equipment
Validation of process including manufacturing/cleaning/sterilizing
The Quality Control Department
Quality Control is done throughout the manufacturing process to ensure that the finished product meets the pre-determined specifications for micro-biological and physiological criteria. Raw materials are specifically tested to ensure the highest level of quality.
The Validation Department
Working closely with the QA and QC departments, the Validation department ensures compliance with all regulations and industry standards. In particular, the main responsibilities of this department are:
Editing of protocols and installation, operation and performance qualification implementation
Validation of HVAC, purified water and other systems
Validation of production of lab equipment
Validation of process including manufacturing/cleaning/sterilizing
Cyto-Matrix Inc. is dedicated to sourcing the highest quality of raw materials available on the global market. It is the combination of high quality raw materials and strictly adhered to GMP practices, which make Cyto-Matrix products of a superior class in the natural health products market.
