GABA (gamma-aminobutyric acid) is a naturally occurring amino acid in the brain and is a major inhibitory neurotransmitter in the central nervous system (CNS). Being an inhibitory neurotransmitter, GABA blocks nerve impulses, slowing down the activity of nerve cells and preventing them from over-firing. Frequent over-firing of brain cells can lead to cell death, meaning that stress can actually kill brain cells. Keeping GABA levels optimal can help prevent this. Thus, GABA serves as a critical calming agent for the body, helping to combat stress and anxiety.
The brain synthesizes GABA from glutamate, an excitatory neurotransmitter. These two neurotransmitters work together in a beautifully orchestrated system of checks and balances. Neurotransmitters are the brain’s basic components of communication, and when there is a breakdown in this communication system, brain function becomes affected. In stressful situations, GABA levels in the body can decrease, and this delicate system becomes out of balance. In a study on humans, prefrontal brain GABA levels decreased by 18% after acute psychological stress, specifically threat of shock (Hasler, G, et al, Am J Psychiatry, 2010). Thus, supplementation with PharmaGABA™, a natural, bioidentical GABA, may be of benefit in helping to cope with stressful situations, whether they arise from daily or extreme stress.
This naturally-sourced GABA is made via a process where the amino acid glutamic acid (glutamate) is
fermented using Lactobacillus hilgardii, the beneficial bacteria also used to ferment many foods including the vegetables in kimchi, the national dish of Korea. PharmaGABA’s chewable tablet delivery allows for rapid and effcient absorption and assimilation. As a result, benefits are felt very quickly.
Who Should Not Take: This product is not recommended for pregnant or lactating women, as well as young children, unless under the guidance of a health care practitioner. Use of PharmaGABA™ may conflict with taking anxiety medications. Most prescription drugs for anxiety work on the GABAergic system since this is known to play an important role in the pathophysiology of anxiety disorders. Do not take PharmaGABA™ with excess alcohol consumption as it may exacerbate the relaxation effect of alcohol drastically.
Recommended Dose: Adults: Take 2 tablets per day, or as directed by your health care practitioner. Consult a health care practitioner for use beyond 3 weeks.
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