Each capsule contains:
Melatonin (N-acetyl-5-methoxytryptamine) 2mg
Lemon balm extract (herb top, Melissa officinalis) 5% rosmarinic acid 125mg
L-theanine 100mg
Valerian extract (root, Valeriana officinalis) 0.8% valerenic acid 56mg
Passionflower extract (herb top, Passiflora incarnata) 10:1, DHE 500mg 50mg
Skullcap extract (herb top, Scutellaria lateriflora) 50mg
GABA (4-Aminobutyric acid) 50mg
60 vegetable capsules
established benefits as a sleep aid
supplement. Clinical trials have found
that melatonin can reduce the time it
takes to fall asleep and improve the
ability to stay asleep, increasing total
sleep time and restfulness. Melatonin
is particularly indicated for individuals
that work irregular day and nighttime
hours or to prevent jet lag
in people that travel often.
Various herbal extracts can support
the use of melatonin and also
support sleep parameters. One of
the best studied herbs for insomnia
is Valeriana officianalis, commonly
known as valerian root. In vitro data
has shown that valerian root may
stimulate gamma-aminobutyric acid
(GABA) release into the brain and
simultaneously block its reuptake.
This may explain why valerian root has
shown comparable effectiveness to a
benzodiazepine medication for sleep
quality after a 4-week intervention,
yet with fewer side effects. One
meta-analysis examined 16 studies for
valerian root on sleep quality, finding a
relative improvement in sleep markers
of 80% compared to placebo in a
subset of trials.
Passiflora incarnata and Melissa
officinalis are two other calming herbs
that have been shown to stimulate
GABA receptors and positively regulate
stress, respectively. Studies examining
Passiflora incarnata have shown that
even just 7 days of consumption as a tea
can improve sleep parameters and that
its supplementation can acutely reduce
stress. Finally, Scutellaria lateriflora
is included for its nervine effects and
GABA-receptor activation, primarily
due to the active ingredient baicalin.
In addition to melatonin and herbal
extracts, amino acids can play a
positive role in alleviating insomnia.
GABA is a well-known inhibitory
neurotransmitter that has been found
to relax the mind and reduce the
amount of time it takes to fall asleep.
Likewise, L-theanine is a single amino
acid, naturally found in green tea, that
is well-known to calm the mind and
improve focus. Research has found
that L-theanine can increase levels of
various neurotransmitters in the brain,
such as serotonin, dopamine and
GABA, while also blocking excitatory
glutamate receptors. Ultimately,
L-theanine increases alpha-brain waves
and improves stress markers such as
Key points
• A formula designed to target
multiple factors that contribute
to insomnia, leading to reduced
sleep latency, less waking and
improved sleep quality
• Melatonin resets the circadian
rhythm and is particularly
indicated for shift-workers or
individuals wanting to prevent
jet lag, capable of improving all
sleep parameters
• Nervine herbal extracts of
Valeriana officianalis, Passiflora
incarnata and Melissa officinalis
are included to positively
modulate the body’s stress
response and to calm the
nervous system
• Amino acids, GABA and
L-theanine, help to acts as an
inhibitory neurotransmitters
that reduces nervous system
excitability, increase alpha-brain
waves and decrease the time
needed to fall asleep
Related products
Sleep.Matrix Ashwagandha
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Theanine
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Magnesium Sleep.Matrix
Melatonin SR 3mg
Melo.Matrix
Relax Matrix
heart rate, blood pressure and salivary
immunoglobulin A.
Each of these aforementioned
ingredients are included in Sleep.Matrix
Melatonin to address multiple possible
causes of poor sleep in individuals
suffering from insomnia. Sleep.Matrix
Melatonin is an evidence-based blend
that is indicated for increasing sleep
latency, duration and quality.
60 vegetable capsules per bottle.
Directions: Adults – Take 1 to 2 capsules per day or as directed by a healthcare
professional. Take a single dose 30 to 60 minutes at or before bedtime. Take an earlier
dose during the evening if necessary. For Jet Lag: Take once a day at bedtime, while
travelling, and at destination until adapted to the new time zone/or daily pattern.
Duration of Use: Consult a healthcare professional for use beyond 4 weeks.
Non-Medicinal Ingredients: Microcrystalline cellulose, magnesium stearate, maltodextrin.
Capsule: hypromellose.
Indications: Helps to speed up the time it takes to fall asleep in people who fall asleep
slowly and helps to temporarily promote relaxation. Helps increase the total sleep time
in people suffering from sleep restriction or altered sleep schedule (e.g. shift-work and
jet lag). Helps re-set the body’s sleep-wake cycle and prevent or reduce the effects of
jet lag (e.g. daytime fatigue, sleep disturbance).
Contraindications: Do not use this product if you are pregnant or breastfeeding.
Do not drive or use machinery for 5 hours after taking melatonin.
Warnings: Do not use if safety seal is broken. Consult a healthcare professional prior
to use, especially if you are taking medications to suppress the immune system
(immunosuppressive medications) or to affect mental state or increase sedation,
steroids or blood thinners, or if you have cardiovascular, immune, liver or chronic kidney
disease. Consult a healthcare professional prior to use if you are taking medications
for seizure or blood pressure, if you have hormonal or seizure disorders, asthma,
depression, diabetes, low blood sugar, or migraine. Consult a healthcare professional
if symptoms persist or worsen or if sleeplessness persists continuously for more than
4 weeks (chronic insomnia). Consumption with alcohol, other medications or health
products with sedative properties is not recommended.
Known Adverse Reactions: Some people may experience drowsiness. Exercise caution
if operating heavy machinery, driving a motor vehicle or involved in activities requiring
mental alertness. Stop use if hypersensitivity/allergy occurs or if you experience
headache, confusion, or nausea.
