Mood-Matrix CytoMatrix

A therapeutic blend of saffron, 5-HTP and GABA with additional B-vitamins and minerals to encourage healthy mood and cognition.
  • A combination of 5-HTP, GABA and saffron, with added cofactor support in the form of targeted and biologically active minerals and vitamins, in order to support healthy mood balance
  • 5-HTP acts as a precursor to serotonin and has been demonstrated to improve mood, sleep difficulties, binge eating, weight management, headaches and fibromyalgia
  • GABA is an inhibitory neurotransmitter used to calm the nervous system and shown to support individuals with high stress and insomnia
  • Saffron (Crocus sativus) has been demonstrated to improve mood, cognition, erectile function and libido in males
  • Zinc, magnesium and activated B-vitamins act as key cofactors in the synthesis and balance of neurotransmitters in the brain
Vegan. GMO, gluten, soy and dairy free.
Available in 90 vegetable capsules.
SKU: 193234
NPN: 80102903
UPC Code: 871740001493

This is a professional line item. If you are unsure of the suitability of this supplement,         Book an appointment with one of our Naturopathic Doctors or consult with a  qualified healthcare practitioner.


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Balanced mental health is a complex and complicated equilibrium to achieve. Although current research surrounding low mood identifies inflammation, hormonal imbalances, social support and many other factors in its etiology, neurotransmitters within the brain cannot be overlooked. Serotonin, GABA (gamma-aminobutyric acid), dopamine and other neurotransmitters all affect an individual’s mental state. As such, any nutrients that can support these brain chemicals have vast therapeutic potential.

5-Hydroxytryptophan (5-HTP) is the well-known precursor to serotonin, a key neurotransmitter involved in mental health, temperature regulation, pain sensation and circadian rhythm regulation through the production of melatonin. 5-HTP is best known for supporting healthy mood, yet its ability to upregulate serotonin may explain why numerous research trials have found that it can also improve sleep difficulties, binge eating, weight management, headaches and fibromyalgia. 5-HTP has long been a staple nutrient for many individuals with low mood.

GABA, on the other hand, is an inhibitory neurotransmitter often used to relax the mind in cases of stress and insomnia. Research has shown that GABA can positively impact cortisol levels and reduce the amount of time it takes to fall asleep, making this amino acid particularly useful in those with difficulty initiating sleep because they cannot calm their racing mind.

Regardless of the targeted neurotransmitter, the body requires specific vitamins and minerals to synthesize and activate each neurotransmitter. For example, vitamin B-6, magnesium and zinc are all required as cofactors for the conversion of 5-HTP into serotonin, while vitamin B-6 and folate are needed for synthesis of dopamine. Understanding these physiological pathways may explain why these nutrients have demonstrated benefits for mood balance either as stand alone agents or in combinations with pharmaceutical medications. Both magnesium and zinc supplementation have been demonstrated to increase brain-derived neurotrophic factor and block NMDA receptors in the brain, augment SSRI therapy and, ultimately, improve subjective markers of mood. Various combinations of
folate, vitamin B-12 and vitamin B-6 have all demonstrated improved mental health outcomes over long-term supplementation.

Mood-Matrix offers a therapeutic and well-balanced blend of targeted amino acids, B-vitamins and minerals in order to support healthy mood balance. Each B-vitamin is provided in its biologically active coenzyme form, while magnesium and zinc are delivered in their highly bioavailable glycinate chelate forms for optimal stability and absorption. In addition to these nutrients, Mood-Matrix strategically includes a standardized extract of saffron to assist in mood support.

Saffron, officially known as crocus sativus, is a traditional spice that isnow known to have multiple health applications. Its ability to block NMDA receptors and protect the nervous system likely explain why saffron has multiple human clinical trials to demonstrate its effectiveness for promoting healthy mood, even when compared to traditional selective-serotonin uptake inhibitor (SSRI) therapy, and also for supporting cognitive function. Saffron has also traditionally been used as an aphrodisiac. Modern research has confirmed that it can effectively improve symptoms of erectile dysfunction and overall sexual function, while also improving sperm parameters.

All in all, Mood-Matrix was formulated to optimally support healthy mood, cognition and neurotransmitter levels in the brain. In essence, Mood-Matrix is a targeted multivitamin-multimineral for the nervous system. Each bottle contains 90 vegetarian capsules.

Ingredient Amount
L-5-HTP (seed, Griffonia simplicifolia) 100mg
GABA (gamma-aminobutyric acid) 33.3mg
Saffron (stigmas, Crocus sativus L., Iridaceae) 5:1 10mg
Vitamin B6 (pyridoxal-5-phosphate) 25mg
Vitamin B12 (methylcobalamin) 33.3mcg
Folate (L-5-methyltetrahydrofolate) 100mcg
Magnesium (Albion™ di-magnesium malate, TRAACS™ magnesium bis-glycinate chelate)* 25mg
Zinc (TRAACS™ zinc bis-glycinate chelate)* 8mg
*Mineral chelates supplied by Albion Laboratories, Inc. AlbionTM, DimaCalTM, TRAACSTM and Albion Gold Medallion design are trademarks of Albion Laboratories,Inc. U.S Patents 6,706,904 7,838,042.

Unit of Measure above: Each capsule contains

Non-Medicinal Ingredients: Glycine, brown rice flour, citric acid, silica, vegetable-grade magnesium stearate, microcrystalline cellulose, maltodextrin. Capsule: hypromellose

Directions: Adults – Take 1 capsule, 3 times per day with food, or as directed by a healthcare professional.

Indications: Helps to promote healthy mood balance and temporarily promote relaxation. Can help to relieve symptoms of fibromyalgia and helps in energy metabolism and tissue formation.

Duration of Use: For use beyond 1 year, consult a healthcare professional. For migraine prophylaxis, use for at least 2 – 3 weeks to see beneficial effects. For mood balance, use for at least 1 week to see beneficial effects. For relief of symptoms of fibromyalgia, use for at least 2 – 3 weeks to see beneficial effects.

Known Adverse Reactions: Some people may experience diarrhea, nausea, vomiting and abdominal pain. Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness.

Warnings: Do not use if safety seal is broken. Consult a healthcare professional prior to use if you are taking carbidopa or drugs or supplements with serotonergic activity. These may include, but are not limited to, L-tryptophan, Sadenosylmethionine (SAMe), St. John’s wort, antidepressants, pain killers, over the counter cough and cold medication containing dextromethorphan, anti-nausea medication and anti-migraine medication. Consult a healthcare professional If you suffer from any psychological disorder or condition, such as frequent anxiety or depression, or if symptoms persist or worsen. Stop use and consult a healthcare professional if you show signs of weakness, oral ulcers, abdominal pain accompanied by severe muscle pain or if you experience skin changes. Avoid taking with alcohol or products that cause drowsiness


Cyto Matix

Why Choose Cyto-Matrix? We are 100% committed to helping you improve lives. Cyto-Matrix's products The excellent clinical results that are achieved with our products, combined with our honest and ethical approach, has earned Cyto-Matrix the trust of many of the most scrutinizing Canadian health care practitioners. We are appreciative and honoured that new clients of Cyto-Matrix quickly become loyal clients and are open to building a lasting relationship with us. Our philosophy is simple; purity, integrity, innovation: Purity Products are developed using the highest grade possible raw materials with vegetable capsules while minimizing the use of excipients. All products are manufactured in state-of-the-art, Good Manufacturing Practices (GMP)-compliant Canadian facilities, meeting or exceeding pharmaceutical and Health Canada standards. Third-Party tested with rigorous QA/QC. Integrity All formulations are researched and designed by Naturopathic Doctors based on Health Canada-approved, evidence based science. Products are fully licensed with approved Health Canada label claims. All associates are required to adhere to the high ethical standards of the organization. Customer Service Representatives will refer technical questions to staff doctors, with accurate, fast-as-possible turn around. Innovation Cyto-Matrix is continually researching and adding cutting-edge formulas to meet the unique and changing needs of your patients. Expertise and innovation are shared through seminars, blog articles and Practice Pearls to aid in professional development and continuing education. Regular feedback from practiticing professionals and our National Advisory Board is an integral part of our innovation. Do share your feedback and ideas! Quality Manufacturing Cyto-Matrix products are manufactured in state-of-the-art Canadian facilities in Quebec and Ontario. Cyto-Matrix's manufacturing facility These facilities hold valid Site Licenses as per the requirements of Health Canada's Natural Health Product Directorate. In accordance with these guidelines, sites must have procedures in place for distribution records and product recalls and for the handling, storage and delivery of their products. They must also demonstrate that they meet Good Manufacturing Practice (GMP) requirements. The Quality Assurance Department This department is responsible for the development of Standard Operating Procedures (SOP's). The main goal here is to ensure the integrity of the result of the finished product. All SOP's ensure compliance with GMP requirements. Other responsibilities include: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing The Quality Control Department Quality Control is done throughout the manufacturing process to ensure that the finished product meets the pre-determined specifications for micro-biological and physiological criteria. Raw materials are specifically tested to ensure the highest level of quality. The Validation Department Working closely with the QA and QC departments, the Validation department ensures compliance with all regulations and industry standards. In particular, the main responsibilities of this department are: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing Cyto-Matrix Inc. is dedicated to sourcing the highest quality of raw materials available on the global market. It is the combination of high quality raw materials and strictly adhered to GMP practices, which make Cyto-Matrix products of a superior class in the natural health products market.


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