SAMe Bioclinic Naturals
SAMe Bioclinic Naturals has several critical physiological functions and is the common thread between three key metabolic pathways. Well-recognized as a unique methyl donor for more than 100 biological reactions, including DNA methylation. It also links methylation to polyamine synthesis (necessary for cell survival and growth) and transsulfuration, which is responsible for cysteine production, the rate-limiting factor in glutathione synthesis. Its unique positioning within these intersecting pathways explain its role as a regulator of redox status, cellular metabolism, proliferation, and apoptosis.
Clinically, it has proven beneficial for a number of conditions, most notably osteoarthritis, fibromyalgia, neurodegenerative disease, depression, and liver disease. For patients with major depressive disorder, SAMe has been shown to be effective not only when compared to standard antidepressants, but also for selective serotonin reuptake inhibitor (SSRI) non-responders. It has also been shown to reduce the incidence of sexual dysfunction which commonly accompanies treatment with SSRI/SNRI therapy. SAMe has also shown efficacy for osteoarthritis comparable to NSAIDs, including celecoxib. Quite importantly, it is likely via increases in cartilage formation, glutathione production, DNA methylation, and gene expression which contribute to its efficacy, a stark contrast from pharmaceutical analgesics. Research also suggests benefit for neurodegenerative disease, and potentially for improving endothelial function.
Medicinal Ingredients
| Each Tablet Contains: |
|
| S-Adenosyl-L-Methionine (SAMe) |
200 mg |
Non-Medicinal Ingredients
Microcrystalline cellulose, mannitol, enteric coating (methacrylic acid copolymer, talc, triethyl citrate, glyceryl palmitostearate, silica, titanium dioxide, medium chain triglycerides, yellow iron oxide), glyceryl behenate, vegetable grade magnesium stearate (lubricant), silica, sodium starch glycolate.
Allergens:
Contains no artificial colours, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Recommended Use:
Recommended Adult Dose: SAMe should always be taken on an empty stomach. For mood balance: 1–4 tablets 2 times per day or as directed by a health care practitioner. For osteoarthritic pain: 1–3 tablets 2 times per day or as directed by a health care practitioner.
Do not exceed a total of 8 tablets per day. SAMe must be taken for a minimum of 2 weeks, at which time effects should be observed.
This is a professional line item. If you are unsure of the suitability of this supplement,
Book an appointment with one of our Naturopathic Doctors or consult with a qualified healthcare practitioner.
Brand
Bioclinic Naturals
At Bioclinic Naturals, we offer an exclusive health care practitioner line of evidence-based natural health products.
Each formula is developed by the industry leading, outstanding scientists and health care practitioners on our Scientific Advisory Board to meet, and exceed, the needs of your patients.
Every great product starts with the best ingredients.
Our goal is to provide the best quality, tested raw materials. We have certified organic farmland in Canada’s Okanagan Valley, and whenever possible we grow our own plant-based ingredients. Any raw material we do not produce ourselves is subjected to the highest level of scrutiny to ensure the quality and purity.
We are Canada’s leading nutraceutical manufacturer.
We have state-of-the-art manufacturing facilities that include tabulating and softgel encapsulation. Our standards meet or surpasses the Canadian Good Manufacturing Practices (GMPs) established by the Natural and Non-Prescription Health Products Directorate (NNHPD) of the Canadian Federal Government, and Canadian Food Inspection Agency (CFIA) regulations. Our products also meet or exceed other international standards including the US Federal Drug Administration (FDA), the US Pharmacopeial Convention (USP), the Korean Ministry of Health and Welfare (MHW), and the Australian Therapeutic Goods Administration (TGA).
Our commitment to quality is reflected in the our investment in expanding our in-house Quality Control, Quality Assurance, and Research & Development departments, allowing us to verify the purity, potency, and efficacy of each and every product. We have advanced analytical technology and equipment, including HPLC and Mass Spectrometry, and can test for over 400 contaminants down to the molecular level. We adhere strictly to good laboratory practices (GLP), and our products are ISURA certified. This third party certification tests for non-GMO, contaminants, and identity.
Bioclinic Naturals’ focus is on clinical application for nutritional interventions and strategies for preventive medicine.
Our unique formulas meet practitioners’ needs for both condition-specific challenges and overall health enhancement. Our continual commitment to product quality in every stage of production for every product ensures that our products have earned the trust of practitioners and their patients.
We work closely with our Scientific Advisory Board to ensure that our products live up to their claims. Their scientific investigation focuses on the clinical application of our products, as well as nutritional interventions and strategies for preventive medicine.
At Bioclinic Naturals, we don’t just say that we provide the most effective natural health products – we prove it. We have the science and clinical research to back up our products for quality, potency, and effectiveness.
