Cyto-Calm 90 v-caps Cytomatrix

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  • SKU: 193136
  • NPN: 80048053
  • UPC: 871740000489
100mg of 5-HTP with biologically active vitamin B6 and L-glycine for complete mood and sleep support.

Indicated for regulating mood, supporting sleep, improving symptoms of fibromyalgia and aiding in weight management

100mg of 5-HTP as a therapeutic amino acid to support the production of serotonin and melatonin

100mg of L-glycine encourages proper cellular signaling in the nervous system to balance mood and improve sleep

10mg of pyridoxal-5-phosphate (P-5-P), the biologically active form of vitamin B6, added for the efficient conversion of 5-HTP into serotonin and the production of other neurotransmitters

Gluten, soy and dairy free.
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The human brain is a complicated structure that relies on multiple chemicals to communicate information. For example, the neurotransmitter serotonin plays a significant role in mental health, temperature regulation and pain sensation, while the hormone melatonin is needed to regulate the circadian rhythm. As one can imagine, any nutrients that can support these brain chemicals have vast therapeutic potential. 5-Hydroxytryptophan (5-HTP) is one such nutrient, as it is the direct precursor to serotonin and, subsequently, melatonin.

5-HTP is most notably used to support healthy mood balance. Yet, its ability to up-regulate serotonin provides application in many other conditions with mental and psychological components. Numerous research trials have found that 5-HTP can also improve sleep difficulties, binge eating, weight management, headaches and fibromyalgia.

The conversion of 5-HTP into serotonin requires vitamin B-6 as a cofactor, just as the synthesis of GABA and dopamine also require vitamin B6. This is thought to explain why vitamin B-6 as a standalone treatment has shown to be beneficial in treating premenstrual symptoms, premenstrual dysphoric disorder and pregnancy-induced nausea. Pyridoxal-5-phosphate (P-5-P) is the coenzyme form of vitamin B6 that is biologically active. Unlike pyridoxine HCl, P-5-P is immediately ready to be used within the nervous system after absorption from the digestive tract.

Glycine acts as another important cellular signal within the brain. Glycine’s role in the nervous system is evident through multiple clinical trials examining the benefits in sleep and obsessive-compulsiveness among other mental conditions. For example, glycine ingestion one hour before sleep has been found to improve sleep latency and quality, reduce morning fatigue and improve next-day cognitive performance.

Cyto·Calm provides a therapeutic combination of 5-HTP, biologically activate vitamin B6 and glycine. Collectively, these nutrients act to support and balance the brain’s neurotransmitters and work synergistically to improve mood and sleep.


Ingredient Amount
L-5-Hydroxytryptophan (seed, Griffonia simplicifolia) 100mg
Vitamin B6 (pyridoxal-5-phosphate) 10mg

Unit of Measure above: Each capsule

Non-Medicinal Ingredients: Glycine, vegetable-grade magnesium stearate, microcrystalline cellulose. Capsule: hypromellose.

Directions and Cautions:

Indications: Helps promote healthy mood balance. Used as a sleep aid.

Directions for Use: Adults – (Healthy Mood Balance) Take 1 capsule, 1-3 times per day with food, or as directed by a healthcare professional. (Sleep Aid) Take 1-2 capsules with food, 30-45 minutes before bedtime, or as directed by a healthcare professional.

Duration of use: Healthy Mood Balance: Use for a minimum of 1 week to see beneficial effects. Consult a healthcare professional for use beyond 1 year

Cautions: Do not use if safety seal is broken. Consult a healthcare professional if symptoms persist or worsen; and prior to use if you are pregnant or nursing, or taking carbidopa or drugs/supplements with serotonergic activity. These may include S-adenosylmethionine (SAMe), St.John’s Wort, antidepressants, pain killers, over the counter cough/cold medication containing dextromethorphan, anti-nausea and anti-migraine medication. Discontinue use and consult healthcare professional if you show signs of weakness, oral ulcer, or abdominal pain accompanied by severe muscle pain or if you experience skin changes. Sleep Aid: Consult healthcare professional if sleeplessness persists for more than 3 weeks.

Contraindications: Do not use if you have scleroderma.

Known Adverse Reactions: Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Some people may experience nausea, diarrhea, vomiting and abdominal pain. Gluten, soy and dairy free.


Cyto Matix

Why Choose Cyto-Matrix? We are 100% committed to helping you improve lives. Cyto-Matrix's products The excellent clinical results that are achieved with our products, combined with our honest and ethical approach, has earned Cyto-Matrix the trust of many of the most scrutinizing Canadian health care practitioners. We are appreciative and honoured that new clients of Cyto-Matrix quickly become loyal clients and are open to building a lasting relationship with us. Our philosophy is simple; purity, integrity, innovation: Purity Products are developed using the highest grade possible raw materials with vegetable capsules while minimizing the use of excipients. All products are manufactured in state-of-the-art, Good Manufacturing Practices (GMP)-compliant Canadian facilities, meeting or exceeding pharmaceutical and Health Canada standards. Third-Party tested with rigorous QA/QC. Integrity All formulations are researched and designed by Naturopathic Doctors based on Health Canada-approved, evidence based science. Products are fully licensed with approved Health Canada label claims. All associates are required to adhere to the high ethical standards of the organization. Customer Service Representatives will refer technical questions to staff doctors, with accurate, fast-as-possible turn around. Innovation Cyto-Matrix is continually researching and adding cutting-edge formulas to meet the unique and changing needs of your patients. Expertise and innovation are shared through seminars, blog articles and Practice Pearls to aid in professional development and continuing education. Regular feedback from practiticing professionals and our National Advisory Board is an integral part of our innovation. Do share your feedback and ideas! Quality Manufacturing Cyto-Matrix products are manufactured in state-of-the-art Canadian facilities in Quebec and Ontario. Cyto-Matrix's manufacturing facility These facilities hold valid Site Licenses as per the requirements of Health Canada's Natural Health Product Directorate. In accordance with these guidelines, sites must have procedures in place for distribution records and product recalls and for the handling, storage and delivery of their products. They must also demonstrate that they meet Good Manufacturing Practice (GMP) requirements. The Quality Assurance Department This department is responsible for the development of Standard Operating Procedures (SOP's). The main goal here is to ensure the integrity of the result of the finished product. All SOP's ensure compliance with GMP requirements. Other responsibilities include: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing The Quality Control Department Quality Control is done throughout the manufacturing process to ensure that the finished product meets the pre-determined specifications for micro-biological and physiological criteria. Raw materials are specifically tested to ensure the highest level of quality. The Validation Department Working closely with the QA and QC departments, the Validation department ensures compliance with all regulations and industry standards. In particular, the main responsibilities of this department are: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing Cyto-Matrix Inc. is dedicated to sourcing the highest quality of raw materials available on the global market. It is the combination of high quality raw materials and strictly adhered to GMP practices, which make Cyto-Matrix products of a superior class in the natural health products market.