Osteoarthritis (OA) is the most common form of joint pain as we age. With a progressive erosion of joint cartilage and resultant inflammation, OA sufferers experience pain, less range of motion and increased stiffness, which can severely impact their quality of life.
There are many natural agents that can be used to improve outcomes with OA patients, but few have more research and years of clinical support than glucosamine, chondroitin, hyaluronic acid and methylsulfonylmethane (MSM). These agents are components of cartilage and synovial fluid, helping to provide shock absorption to the joint and decrease friction with movement. For example, glucosamine is produced naturally by chondrocytes and is necessary to make glycosaminoglycans, a core component of cartilage. Hyaluronic acid is a central component of synovial fluid. Glucosamine sulfate, in particular, has been shown to stimulate the anabolic process of cartilage metabolism and improve clinical outcomes more efficiently than glucosamine HCl.
Hydrolyzed collagen is clinically researched to support joint health. Studies show that collagen peptides provide the building blocks needed to make joint cartilage and they upregulate chondrocyte activity, increase hyaluronic acid production and improve microcirculation. Clinical trials have found that collagen peptides can improve activity-related knee pain in healthy athletes and also knee and hip pain during rest and activity in middle-aged individuals. Vitamin C may augment these benefits as it is a necessary cofactor in the collagen production process.
Natural anti-inflammatory herbs such as curcuma longa, boswellia serrata, zingiber officinale, harpagophytum procumbens and withania somnifera also play a role in the management of OA. Multiple human clinical trials have confirmed that these herbs have pain-reducing properties and that they can benefit individuals with OA Curcuma longa contains active ingredients known as curcuminoids, which have been shown to inhibit NF-Kappa B and TNF-alpha under chronic inflammatory conditions. Research trials have shown that curcuminoids can decrease the need for pain-killing medications such as acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) in OA sufferers. They can also decrease post-exercise muscle soreness. In addition to its anti-inflammatory action on NF-Kappa B and TNF-alpha, curcuminoids have been found to inhibit matrix metalloproteinase-3, an enzyme known to degrade cartilage. This means that it is both improving symptoms and protecting the joints from further damage. Joint Matrix Liquid specifically uses a patented blend of curcuminoids that is standardized to minimum 95% curcuminoid content of curcumin, BDMC and DMC. This patented curcuminoid blend, known as uC3 Clear Complex, has more than 80 research papers and more than 45 clinical studies to support its efficacy and safety.
Boswellia’s clinical benefits for OA stem from its boswellic acid content and its ability to inhibit matrix metalloproteinase-3 and 5-lipoxygenase (5-LOX). Standardized boswellia extracts can decrease pain, reduce swelling and increase range of motion. One trial found that boswellia was as effective as the NSAID medication valdecoxib for the relief of OA symptoms.
Cyto-Matrix’s Joint Matrix Liquid contains a blend of 11 evidence-based nutrients and herbs to decrease symptoms in OA sufferers, protect the joint from further damage and decrease the need for anti-inflammatory pharmaceutical medications.
Joint Matrix Liquid manages to provide evidence-based doses and standardized extracts all in just a dose of one tablespoon per day, allowing for superior clinical outcomes and high compliance in your patients. Simply put, it is rare to find such a comprehensive blend of well-researched nutrients for joint health in a single natural health product.
| Ingredient | Amount |
|---|---|
| Hydrolyzed collagen (bovine) | 1800mg |
| Glucosamine sulfate | 1500mg |
| Methylsulfonylmethane (MSM) | 750mg |
| Ginger extract (rhizome, zingiber officinale) 8:1 | 100mg |
| Ashwagandha extract (whole plant) 5:1 | 200mg |
| Devil’s claw extract (root tuber, harpagophytum procumbens) 4:1 | 500mg |
| uC3 Clear™ (curcumin, curcuma longa)* | 50mg |
| Boswellia extract (resin, boswellia serrata) 10:1 | 100mg |
| Hyaluronic acid (sodium hyaluronate) | 50mg |
| Zinc (TRAACS® Zinc Bis-glycinate Chelate)** | 15mg |
| Vitamin C (ascorbic acid) | 30mg |
| **Mineral chelate supplied by Albion Laboratories, Inc. TRAACS® and the Albion Gold Medallion design are registered trademarks of Albion Laboratories, Inc. Chelate covered by U.S. Patent 7,838,042. | |
| *uC3 Clear™ is a registered trademark of Sabinsa Corp. |
Unit of Measure above: Each tablespoon (15ml)
Non-Medicinal Ingredients: Purified water, sorbitol, glycerin, xylitol, natural green apple flavour, DL-malic acid, potassium sorbate, xanthan gum, monk fruit extract, citrus extract, povidone K-30, licorice root extract.
Directions: Adults – Take 1 tablespoon (15ml) per day or as directed by a healthcare professional. Shake before use. Refrigerate after opening.
Duration of Use: Use for a minimum of 1 month to see beneficial effects.
Indications: A factor in maintaining healthy cartilage and/or joint health. Helps to reduce joint pain associated with osteoarthritis.
Warnings: Do not use if safety seal is broken. Consult a healthcare professional on the use of this product, especially if symptoms persist or worsen; and prior to use if you are pregnant, breastfeeding, or taking medications including antiplatelet medication or blood thinners, or have a medical condition including gallstones, bile duct obstruction, allergies to shellfish, stomach ulcers, or excess stomach acid. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended.
Known Adverse Reactions: Hypersensitivity (e.g. allergy) has been known to occur and some people may experience mild gastrointestinal disturbances such as diarrhoea, abdominal pain, heartburn, nausea, and vomiting; in which case, discontinue use.
