Joint-Matrix Liquid CytoMatrix

A comprehensive blend of 11 evidence-based nutrients to support joint health, delivered in a liquid format.
  • Provides one of the most comprehensive blends of well-researched nutrients to decrease symptoms of osteoarthritis, protect joints from further damage and reduce the need for prescription or over-the-counter pain medications
  • Contains a blend of glucosamine sulfate, chondroitin sulphate, hyaluronic acid, methylsulfonylmethane (MSM) and hydrolyzed collagen to collectively improve articular cartilage and synovial fluid production in the joints
  • Boswellia serrata, zingiber officinale, harpagophytum procumbens and withania somnifera are all delivered as highly potent extracts to yield therapeutic amounts of active ingredients and offer powerful anti-inflammatory actions
  • Curcumin is provided as the highly standardized and well-researched uC3 Clear Complex, providing minimum 95% curcuminoid content
  • Added vitamin C to support the healthy production of collagen and zinc is provided in the full glycinate chelate form (patented TRAACS delivery) for optimal absorption
  • Liquid delivery and natural green apple flavour allow for greater patient compliance
GMO, gluten, soy and dairy-free.
450ml bottle
SKU: 193184
NPN: 80085524
UPC Code: 871740000991

This is a professional line item. If you are unsure of the suitability of this supplement,         Book an appointment with one of our Naturopathic Doctors or consult with a  qualified healthcare practitioner.


Osteoarthritis (OA) is the most common form of joint pain as we age. With a progressive erosion of joint cartilage and resultant inflammation, OA sufferers experience pain, less range of motion and increased stiffness, which can severely impact their quality of life.

There are many natural agents that can be used to improve outcomes with OA patients, but few have more research and years of clinical support than glucosamine, chondroitin, hyaluronic acid and methylsulfonylmethane (MSM). These agents are components of cartilage and synovial fluid, helping to provide shock absorption to the joint and decrease friction with movement. For example, glucosamine is produced naturally by chondrocytes and is necessary to make glycosaminoglycans, a core component of cartilage. Hyaluronic acid is a central component of synovial fluid. Glucosamine sulfate, in particular, has been shown to stimulate the anabolic process of cartilage metabolism and improve clinical outcomes more efficiently than glucosamine HCl.

Hydrolyzed collagen is clinically researched to support joint health. Studies show that collagen peptides provide the building blocks needed to make joint cartilage and they upregulate chondrocyte activity, increase hyaluronic acid production and improve microcirculation. Clinical trials have found that collagen peptides can improve activity-related knee pain in healthy athletes and also knee and hip pain during rest and activity in middle-aged individuals. Vitamin C may augment these benefits as it is a necessary cofactor in the collagen production process.

Natural anti-inflammatory herbs such as curcuma longa, boswellia serrata, zingiber officinale, harpagophytum procumbens and withania somnifera also play a role in the management of OA. Multiple human clinical trials have confirmed that these herbs have pain-reducing properties and that they can benefit individuals with OA Curcuma longa contains active ingredients known as curcuminoids, which have been shown to inhibit NF-Kappa B and TNF-alpha under chronic inflammatory conditions. Research trials have shown that curcuminoids can decrease the need for pain-killing medications such as acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) in OA sufferers. They can also decrease post-exercise muscle soreness. In addition to its anti-inflammatory action on NF-Kappa B and TNF-alpha, curcuminoids have been found to inhibit matrix metalloproteinase-3, an enzyme known to degrade cartilage. This means that it is both improving symptoms and protecting the joints from further damage. Joint Matrix Liquid specifically uses a patented blend of curcuminoids that is standardized to minimum 95% curcuminoid content of curcumin, BDMC and DMC. This patented curcuminoid blend, known as uC3 Clear Complex, has more than 80 research papers and more than 45 clinical studies to support its efficacy and safety.

Boswellia’s clinical benefits for OA stem from its boswellic acid content and its ability to inhibit matrix metalloproteinase-3 and 5-lipoxygenase (5-LOX). Standardized boswellia extracts can decrease pain, reduce swelling and increase range of motion. One trial found that boswellia was as effective as the NSAID medication valdecoxib for the relief of OA symptoms.

Cyto-Matrix’s Joint Matrix Liquid contains a blend of 11 evidence-based nutrients and herbs to decrease symptoms in OA sufferers, protect the joint from further damage and decrease the need for anti-inflammatory pharmaceutical medications.

Joint Matrix Liquid manages to provide evidence-based doses and standardized extracts all in just a dose of one tablespoon per day, allowing for superior clinical outcomes and high compliance in your patients. Simply put, it is rare to find such a comprehensive blend of well-researched nutrients for joint health in a single natural health product.

Ingredient Amount
Hydrolyzed collagen (bovine) 1800mg
Glucosamine sulfate 1500mg
Methylsulfonylmethane (MSM) 750mg
Ginger extract (rhizome, zingiber officinale) 8:1 100mg
Ashwagandha extract (whole plant) 5:1 200mg
Devil’s claw extract (root tuber, harpagophytum procumbens) 4:1 500mg
uC3 Clear™ (curcumin, curcuma longa)* 50mg
Boswellia extract (resin, boswellia serrata) 10:1 100mg
Hyaluronic acid (sodium hyaluronate) 50mg
Zinc (TRAACS® Zinc Bis-glycinate Chelate)** 15mg
Vitamin C (ascorbic acid) 30mg
**Mineral chelate supplied by Albion Laboratories, Inc. TRAACS® and the Albion Gold Medallion design are registered trademarks of Albion Laboratories, Inc. Chelate covered by U.S. Patent 7,838,042.
*uC3 Clear™ is a registered trademark of Sabinsa Corp.

Unit of Measure above: Each tablespoon (15ml)

Non-Medicinal Ingredients: Purified water, sorbitol, glycerin, xylitol, natural green apple flavour, DL-malic acid, potassium sorbate, xanthan gum, monk fruit extract, citrus extract, povidone K-30, licorice root extract.

Directions: Adults – Take 1 tablespoon (15ml) per day or as directed by a healthcare professional. Shake before use. Refrigerate after opening.

Duration of Use: Use for a minimum of 1 month to see beneficial effects.

Indications: A factor in maintaining healthy cartilage and/or joint health. Helps to reduce joint pain associated with osteoarthritis.

Warnings: Do not use if safety seal is broken. Consult a healthcare professional on the use of this product, especially if symptoms persist or worsen; and prior to use if you are pregnant, breastfeeding, or taking medications including antiplatelet medication or blood thinners, or have a medical condition including gallstones, bile duct obstruction, allergies to shellfish, stomach ulcers, or excess stomach acid. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended.

Known Adverse Reactions: Hypersensitivity (e.g. allergy) has been known to occur and some people may experience mild gastrointestinal disturbances such as diarrhoea, abdominal pain, heartburn, nausea, and vomiting; in which case, discontinue use.


Cyto Matix

Why Choose Cyto-Matrix? We are 100% committed to helping you improve lives. Cyto-Matrix's products The excellent clinical results that are achieved with our products, combined with our honest and ethical approach, has earned Cyto-Matrix the trust of many of the most scrutinizing Canadian health care practitioners. We are appreciative and honoured that new clients of Cyto-Matrix quickly become loyal clients and are open to building a lasting relationship with us. Our philosophy is simple; purity, integrity, innovation: Purity Products are developed using the highest grade possible raw materials with vegetable capsules while minimizing the use of excipients. All products are manufactured in state-of-the-art, Good Manufacturing Practices (GMP)-compliant Canadian facilities, meeting or exceeding pharmaceutical and Health Canada standards. Third-Party tested with rigorous QA/QC. Integrity All formulations are researched and designed by Naturopathic Doctors based on Health Canada-approved, evidence based science. Products are fully licensed with approved Health Canada label claims. All associates are required to adhere to the high ethical standards of the organization. Customer Service Representatives will refer technical questions to staff doctors, with accurate, fast-as-possible turn around. Innovation Cyto-Matrix is continually researching and adding cutting-edge formulas to meet the unique and changing needs of your patients. Expertise and innovation are shared through seminars, blog articles and Practice Pearls to aid in professional development and continuing education. Regular feedback from practiticing professionals and our National Advisory Board is an integral part of our innovation. Do share your feedback and ideas! Quality Manufacturing Cyto-Matrix products are manufactured in state-of-the-art Canadian facilities in Quebec and Ontario. Cyto-Matrix's manufacturing facility These facilities hold valid Site Licenses as per the requirements of Health Canada's Natural Health Product Directorate. In accordance with these guidelines, sites must have procedures in place for distribution records and product recalls and for the handling, storage and delivery of their products. They must also demonstrate that they meet Good Manufacturing Practice (GMP) requirements. The Quality Assurance Department This department is responsible for the development of Standard Operating Procedures (SOP's). The main goal here is to ensure the integrity of the result of the finished product. All SOP's ensure compliance with GMP requirements. Other responsibilities include: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing The Quality Control Department Quality Control is done throughout the manufacturing process to ensure that the finished product meets the pre-determined specifications for micro-biological and physiological criteria. Raw materials are specifically tested to ensure the highest level of quality. The Validation Department Working closely with the QA and QC departments, the Validation department ensures compliance with all regulations and industry standards. In particular, the main responsibilities of this department are: Editing of protocols and installation, operation and performance qualification implementation Validation of HVAC, purified water and other systems Validation of production of lab equipment Validation of process including manufacturing/cleaning/sterilizing Cyto-Matrix Inc. is dedicated to sourcing the highest quality of raw materials available on the global market. It is the combination of high quality raw materials and strictly adhered to GMP practices, which make Cyto-Matrix products of a superior class in the natural health products market.


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